Who we are

Meet the team

Alex Diamantopoulos, MSc

Managing Director

Alex is the Director and founder of Symmetron.

He has expertise in many areas of health economic evaluation. He has developed studies and provided strategic advice to help many companies overcoming the challenges in generating, synthesising and evaluating health economic evidence in order to achieve market access. He has designed economic evaluations and other market access tools in Europe, USA, Canada, Australia and several countries of East Asia.

His research interests include decision-analytic modelling, use of statistical methods in economic evaluations and indirect treatment comparisons. He has completed research in a range of therapeutic areas including oncology, diabetes, rheumatoid arthritis, heart disease, mental health and behavioural conditions, neurological conditions, paediatric diseases, diagnostics, and various applications of medical devices. An economist by training, Alex has an MSc from the University of Birmingham.

The Cancer Drugs Fund in Practice and Under the New Framework
Oncology
The Cancer Drugs Fund in Practice and Under the New Framework
Alex Diamantopoulos, MSc
2023
The Burden of Illness of Idiopathic Pulmonary Fibrosis: A Comprehensive Evidence Review
Respiratory
The Burden of Illness of Idiopathic Pulmonary Fibrosis: A Comprehensive Evidence Review
Alex Diamantopoulos, MSc
Emily Wright
2023
The Challenges of Outcomes-Based Contract Implementation for Medicines in Europe
Policy and methods
The Challenges of Outcomes-Based Contract Implementation for Medicines in Europe
Alex Diamantopoulos, MSc
2022
Using Data on Survival with Idiopathic Pulmonary Fibrosis to Estimate Survival with Other Types of Progressive Fibrosis Interstitial Lung Disease: A Bayesian Framework
Respiratory
Using Data on Survival with Idiopathic Pulmonary Fibrosis to Estimate Survival with Other Types of Progressive Fibrosis Interstitial Lung Disease: A Bayesian Framework
Alex Diamantopoulos, MSc
Claudia Rinciog, MSc
2021
Cost-effectiveness of an insertable cardiac monitor to detect atrial fibrillation in patients with cryptogenic stroke
Cardiometabolic health
Cost-effectiveness of an insertable cardiac monitor to detect atrial fibrillation in patients with cryptogenic stroke
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2020
Cost-effectiveness Analysis of Nintedanib Versus Pirfenidone in Idiopathic Pulmonary Fibrosis in Belgium
Respiratory
Cost-effectiveness Analysis of Nintedanib Versus Pirfenidone in Idiopathic Pulmonary Fibrosis in Belgium
Alex Diamantopoulos, MSc
Claudia Rinciog, MSc
2020
Tofacitinib for the treatment of moderately to severely active ulcerative colitis: a systematic review, network meta-analysis and economic evaluation.
Arthritis and immunology
Tofacitinib for the treatment of moderately to severely active ulcerative colitis: a systematic review, network meta-analysis and economic evaluation.
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2019
Cost effectiveness of an insertable cardiac monitor in a high-risk population in the UK
Cardiometabolic health
Cost effectiveness of an insertable cardiac monitor in a high-risk population in the UK
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
Claudia Rinciog, MSc
2019
A Cost-Effectiveness Analysis of Nintedanib in Idiopathic Pulmonary Fibrosis in the UK
Respiratory
A Cost-Effectiveness Analysis of Nintedanib in Idiopathic Pulmonary Fibrosis in the UK
Alex Diamantopoulos, MSc
Claudia Rinciog, MSc
2017
Tocilizumab in Methotrexate-Naive Rheumatoid Arthritis – A Cost-Utility Model for Slovakia
Arthritis and immunology
Tocilizumab in Methotrexate-Naive Rheumatoid Arthritis – A Cost-Utility Model for Slovakia
Laura Sawyer, MSc
Alex Diamantopoulos, MSc
2015
Tocilizumab in the Treatment of Rheumatoid Arthritis: A Cost-Effectiveness Analysis in the UK
Arthritis and immunology
Tocilizumab in the Treatment of Rheumatoid Arthritis: A Cost-Effectiveness Analysis in the UK
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2014
Mabthera (Rituximab) for the Treatment of Severe Granulomatosis With Polyangiitis (Gpa) and Microscopic Polyangiitis (Mpa) – A Cost-Utility Model for the United Kingdom
Rare diseases
Mabthera (Rituximab) for the Treatment of Severe Granulomatosis With Polyangiitis (Gpa) and Microscopic Polyangiitis (Mpa) – A Cost-Utility Model for the United Kingdom
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2014
Efficacy Of Novel Dmards In Early Active Rheumatoid Arthritis: An Indirect Comparison
Arthritis and immunology
Efficacy Of Novel Dmards In Early Active Rheumatoid Arthritis: An Indirect Comparison
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2014
An Indirect Treatment Comparison of Cabozantinib Verse Vandetanib in Progressive Medullary Thyroid Cancer (MTC)
Oncology
An Indirect Treatment Comparison of Cabozantinib Verse Vandetanib in Progressive Medullary Thyroid Cancer (MTC)
Alex Diamantopoulos, MSc
Claudia Rinciog, MSc
2014
Cost-utility of tocilizumab in the treatment of systemic juvenile idiopathic arthritis in Finland
Arthritis and immunology
Cost-utility of tocilizumab in the treatment of systemic juvenile idiopathic arthritis in Finland
Alex Diamantopoulos, MSc
2013
Cost-effectiveness impact of rivaroxaban versus new and existing prophylaxis for the prevention of venous thromboembolism after total hip or knee replacement surgery in France, Italy and Spain
Cardiometabolic health
Cost-effectiveness impact of rivaroxaban versus new and existing prophylaxis for the prevention of venous thromboembolism after total hip or knee replacement surgery in France, Italy and Spain
Alex Diamantopoulos, MSc
2013
Tocilizumab in Polyarticular Juvenile Idiopathic Arthritis – A Cost-Utility Model for the United Kingdom
Arthritis and immunology
Tocilizumab in Polyarticular Juvenile Idiopathic Arthritis – A Cost-Utility Model for the United Kingdom
Laura Sawyer, MSc
Alex Diamantopoulos, MSc
2013
Validity of cost and utility results?
Policy and methods
Validity of cost and utility results?
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2012
Cost-effectiveness of rivaroxaban in the prevention of venous thromboembolism: A Canadian analysis using the Ontario Ministry of Health Perspective
Cardiometabolic health
Cost-effectiveness of rivaroxaban in the prevention of venous thromboembolism: A Canadian analysis using the Ontario Ministry of Health Perspective
Alex Diamantopoulos, MSc
2012
Economic evaluation of tocilizumab combination in the treatment of moderate to severe rheumatoid arthritis in Italy
Arthritis and immunology
Economic evaluation of tocilizumab combination in the treatment of moderate to severe rheumatoid arthritis in Italy
Alex Diamantopoulos, MSc
2012
Cost Effectiveness of Rivaroxaban versus Enoxaparin for Prevention of Post-Surgical Venous Thromboembolism from a US Payer’s Perspective
Cardiometabolic health
Cost Effectiveness of Rivaroxaban versus Enoxaparin for Prevention of Post-Surgical Venous Thromboembolism from a US Payer’s Perspective
Alex Diamantopoulos, MSc
2012
Cost and outcomes associated with rivaroxaban vs enoxaparin for the prevention of postsurgical venous thromboembolism from a US payer’s perspective
Cardiometabolic health
Cost and outcomes associated with rivaroxaban vs enoxaparin for the prevention of postsurgical venous thromboembolism from a US payer’s perspective
Alex Diamantopoulos, MSc
2012
Cost-effectiveness of rivaroxaban versus heparins for prevention of venous thromboembolism after total hip or knee surgery in Sweden
Cardiometabolic health
Cost-effectiveness of rivaroxaban versus heparins for prevention of venous thromboembolism after total hip or knee surgery in Sweden
Alex Diamantopoulos, MSc
2012
An indirect comparison, via enoxaparin, of rivaroxaban with dabigatran in the prevention of venous thromboembolism after hip or knee replacement
Cardiometabolic health
An indirect comparison, via enoxaparin, of rivaroxaban with dabigatran in the prevention of venous thromboembolism after hip or knee replacement
Alex Diamantopoulos, MSc
2011
Cost-Effectiveness of Rivaroxaban versus Enoxaparin for the Prevention of Postsurgical Venous Thromboembolism in Canada
Cardiometabolic health
Cost-Effectiveness of Rivaroxaban versus Enoxaparin for the Prevention of Postsurgical Venous Thromboembolism in Canada
Alex Diamantopoulos, MSc
2010
UK cost-utility analysis of rituximab in patients with rheumatoid arthritis that failed to respond adequately to a biologic disease-modifying antirheumatic drug
Arthritis and immunology
UK cost-utility analysis of rituximab in patients with rheumatoid arthritis that failed to respond adequately to a biologic disease-modifying antirheumatic drug
Alex Diamantopoulos, MSc
2008
An economic evaluation of cetuximab combined with radiotherapy for patients with locally advanced head and neck cancer in Belgium, France, Italy, Switzerland and the United Kingdom
Oncology
An economic evaluation of cetuximab combined with radiotherapy for patients with locally advanced head and neck cancer in Belgium, France, Italy, Switzerland and the United Kingdom
Alex Diamantopoulos, MSc
2008
A lifetime modelled economic evaluation comparing pioglitazone and rosiglitazone for the treatment of type 2 diabetes mellitus in the UK
Cardiometabolic health
A lifetime modelled economic evaluation comparing pioglitazone and rosiglitazone for the treatment of type 2 diabetes mellitus in the UK
Alex Diamantopoulos, MSc
2007

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Training and workshops
Statistical analysis
Medical writing
Health technology assessment
Health economic modelling
Evidence development