Vacancy: Senior Statistician

Close date: 9 am, Monday, 06 January 2025. Shortlisting and interviews will happen on a rolling basis so early application is encouraged. We may close this vacancy early if a suitable candidate is found.

Who we are, who we are looking for and what we offer

Symmetron has over 15 years of business activity in health economics and outcomes research (HEOR), providing solutions for major pharmaceutical companies and medical device manufacturers worldwide. We promote a culture of creativity, independent thinking, teamwork and scientific excellence.

We are looking for a Senior Statistician with exceptional attention to detail and a passion for data analysis using advanced or innovative methods to join our multidisciplinary team. This job is an opportunity for a driven, enthusiastic individual with a keen interest in Health Technology Assessment (HTA). Through independent work or the coordination and supervision of other researchers, the successful candidate will provide statistical and analytical expertise, devise statistical analysis plans, perform data analysis, and interpret and write up results.

The successful candidate will deliver high-quality statistical work across different projects in a wide range of therapeutic areas. Typical projects could involve performing regression analyses using individual patient-level data from clinical trials or registries, survival analysis to extrapolate long-term results and Bayesian network meta-analysis (NMA) to indirectly compare different interventions. The senior statistician should keep up to date on the latest developments in the field and feel comfortable suggesting and exploring novel methods when relevant.

We are committed to the personal development of our employees and offer excellent training and career development opportunities. Symmetron was awarded the Investors In People accreditation in 2021, with 100% of our team agreeing Symmetron was a great place to work. Our company offers excellent benefits, including but not limited to:

• A very competitive base salary, pension scheme and annual performance-related discretionary bonus.
• Professional development opportunities, within a friendly and supportive team, with access to our tailored internal training programme and external training as needed.
• A hybrid and flexible mix of home and in-office working.
• Life and private health insurance.
• Access to free confidential well-being advice via our employee assistance programme.
• A cycle to work scheme.
• Eye care contribution.
• A wealth of policies that cover enhanced parental leave, compassionate bereavement leave, and temporary remote working for an extended time.

Key responsibilities

• Independently conduct and oversee statistical analyses as stand-alone projects or to feed into economic models or HTA submissions (e.g. NICE or SMC submissions).
• Work with colleagues to scope new projects, lead development of statistical analysis plans and research new methods relevant to our work.
• Liaise with health economics and health outcomes colleagues to ensure statistical analyses are aligned with expectations across different teams, and when required, train and mentor colleagues on statistical processes and software.
• Liaise with external statisticians, programmers and methodologists to communicate work plans and to validate methodological approaches.
• Be responsible for the development of slide decks, study reports, manuscripts, posters and other publications related to health economics and outcomes research.
• Confidently interact with clients on a regular basis, being able to provide written clarification to technical queries, present methods and results at client meetings.
• Be responsible for the day-to-day management of projects and for quality assurance activities (i.e. so that deliverables are provided at an excellent standard).
• Provide support or leadership on components of business development activities, including development of proposals for new projects.
• Proactively undertake continuous professional development and learning activities, including assisting, mentoring or line managing other team members.

The above is not an exhaustive list of duties, and you will be expected to perform different tasks as necessitated by the organisation's overall business objectives.

Essential requirements and qualifications

• Postgraduate degree in statistics, mathematics or a scientific field with a focus on data analysis.
• Proven experience as a statistician or data analyst in a commercial or academic setting.
• Confidence in using WinBUGS (or a similar NMA software) and R.
• A willingness to trial, explore or recommend new software that may suit specific projects with limited guidance.
• Excellent oral and written communication skills and the ability to explain complex statistical methodology and results to a non-expert audience.
• A genuine interest in HTA, systematic review, evidence synthesis, critical appraisal, health economics and statistics.
• Excellent writing skills (development of presentations, reports, dossiers, manuscripts).
• Excellent accuracy and attention to detail, along with the ability to maintain high quality deliverables given competing demands and changing deadlines.
• An organised and methodological approach to planning and delivering work of high quality, taking responsibility for management of small projects or subcomponents of larger projects.
• Strong quantitative, critical thinking and analytical skills; able to review and assimilate large amounts of scientific information under a deadline.
• Ability to in a team-oriented environment and independently, taking responsibility for assigned project work, with effective delegation and/or supervision of tasks undertaken by other team members.
• High self-motivation, can-do attitude, optimistic outlook and leadership ability.
• Initiative to learn new skills, and develop the skill set of others with less experience.
• Excellent computer literacy, and proficiency using Microsoft Office and reference management software.

Desirable skills and experience

These are nice-to-have skills. Candidates that do not fulfil these requirements but have an interest in this role are encouraged to apply.

• Experience in conducting Bayesian network meta-analyses and survival analyses from inception to reporting phase.
• Experience with handling patient level data and large databases, medical claims databases, registries etc.
• Experience using SAS and/or Stata.
• Experience in and/or knowledge of HTA processes.
• Project management experience.
• Experience in and/or knowledge of clinical processes or trials.
• Interest in publication and conference attendance, with some publication history.
• Mentorship or line management experience.
• Business development experience.

Application process

• After the upload of your CV, we ask you to fill in a brief questionnaire.

• Candidates successful in this first round will be contacted to undertake an non-timed exercise (remotely) to demonstrate the knowledge and skills required for the role.

• Shortlisted applicants may also be invited for an initial phone call before the final interview stage.

Please Note:

• This job is a full-time position based in our offices in Central London. Working from home is supported and organised around staff roles and responsibilities.
• No agencies, please.

‍

Who are we?

Symmetron is a health economics and outcomes research consultancy with over 15 years of business activity in health economics and outcomes research (HEOR), providing solutions for major pharmaceutical companies and medical device manufacturers worldwide. We promote a culture of creativity, independent thinking, team-work and scientific excellence.

We are committed to the personal development of our employees and offer excellent training and career development opportunities, inclusive of opportunities to pursue research interests. Our company offers a very competitive base salary, access to a bonus scheme and excellent benefits.

Who are we looking for?

We are looking for a Senior Health Economist with exceptional attention to detail to join our team. This job is an opportunity for a driven, enthusiastic individual with a keen interest in the technical application of health economic research methods, while advancing their project management, leadership and strategic consulting skills. The ideal candidate will be passionate about the delivery of high-quality economic models and critique of the evidence to understand the value of new medical advancements. The successful candidate will participate in all aspects of health economic research, performing clinical and economic evidence review, synthesis of inputs (inclusive of survival analysis and network meta-analysis), model development and communication. Thought leadership is encouraged, with opportunities to pursue research interests, attend conferences and publication.

Key responsibilities

• Design, develop and adapt economic models using international best practice guidelines, supervising the day-to-day activities of less experienced health economists working alongside you.
• Review and critically appraise health economic evidence.
• Work with systematic reviewing colleagues to scope new projects, as well as advise on protocols and search strategies to identify necessary evidence for health economic models.
• Be responsible for the development of slide decks, study reports, manuscripts, posters and other publications related to health economics and outcomes research.
• Confidently interact with clients on a regular basis, being able to provide written clarification to technical queries, present methods and results at client meetings.
• Be responsible for the day-to-day management of projects and for quality assurance activities (i.e. so that deliverables are provided at an excellent standard).
• Provide support or leadership on components of business development activities, including development of proposals for new projects.
• Proactively undertake continuous professional development and learning activities, including assisting, mentoring or line managing other team members.

The above is not an exhaustive list of duties, and you will be expected to perform different tasks as necessitated by the organisation's overall business objectives.

Essential requirements and qualifications

• Professional experience of applying health economic and mathematical modelling techniques in a commercial or academic setting.
• Excellent technical expertise in the development, audit and critical assessment of health economic evaluation and models, with advanced skills in Excel (including experience of VBA).
• A genuine interest and good understanding of statistical concepts and critical review of scientific literature.
• Demonstrated knowledge and experience with the evidentiary requirements for submissions to health technology assessment (HTA) bodies (e.g. the National Institute for Health and Care Excellence).
• Excellent oral and written communication skills, with the ability to effectively engage with a wide-ranging audience and explain complex modelling techniques and results.
• Excellent writing skills (development of presentations, reports, dossiers, manuscripts).
• Excellent accuracy and attention to detail, along with the ability to maintain high quality deliverables given competing demands and changing deadlines.
• An organised and methodological approach to planning and delivering work of high quality, taking responsibility for management of small projects or subcomponents of larger projects.
• Strong quantitative, critical thinking and analytical skills, and able to review and assimilate large amounts of scientific information under a deadline.
• Ability to in a team-oriented environment and independently, taking responsibility for assigned project work, with effective delegation and/or supervision of tasks undertaken by other team members.
• High self-motivation, can-do attitude, optimistic outlook and leadership ability.
• Initiative to learn new skills, and develop the skill set of others with less experience.
• Excellent computer literacy, and proficiency using Microsoft Office and reference management software.

Desirable skills and experience

These are nice-to-have skills. Candidates who do not fulfil these requirements but are interested in this role are encouraged to apply.

• Experience conducting systematic reviews and/or meta-analyses.
• Experience with statistical and economic modelling software (e.g. R, Treeage, WinBUGS, SAS, Stata).
• Understanding of advanced statistical methods and concepts for evidence synthesis or modelling, e.g. indirect treatment comparison and network meta-analysis methods, survival analysis.
• Project management experience.
• Experience in and/or knowledge of clinical processes or trials.
• Interest in publication and conference attendance, with some publication history.
• Mentorship or line management experience.
• Business development experience.
  

Application process

• Candidates successful in this first round will be contacted to attend an introductory phone call with a member of the Symmetron health economics team.

Please note:

• This job is a full-time position based in our offices in Central London. Working from home is supported and organised around staff roles and responsibilities.
• No agencies, please.

‍

‍Shortlisting and interviews will happen on a rolling basis so early application is encouraged. We may close this vacancy if a suitable candidate is found.

Who are we?

Symmetron is a health economics and outcomes research consultancy with over a decade of experience in evidence generation, decision-analytic modelling and statistical analysis. Our experience involves designing, developing, and communicating solutions for major pharmaceutical companies and medical device manufacturers, both at a global and regional level. We promote a culture of creativity, independent thinking, team-work and scientific excellence.

We are committed to the personal development of our employees and offer excellent training and career development opportunities, inclusive of opportunities to pursue research interests. Our company offers a very competitive base salary, access to a bonus scheme and excellent benefits.

Who are we looking for?

We are looking for an exceptional Health Economics Manager to join the team. This is an opportunity for a driven, enthusiastic individual with broad technical knowledge and a keen interest to lead on the technical and project management of our high-quality economic models to evaluate health care interventions. Our health economics team primarily focuses on developing economic models and critiquing the existing evidence base to understand the value of new medical advancements. The candidate will lead, supervise and offer support to less experienced staff in all aspects of health economic research, performing clinical and economic evidence review, synthesis of inputs, model development and communication.

Key responsibilities

• Provide leadership and project management on health economics modelling projects across a wide range of therapeutic areas.
• Provide technical expertise and develop conceptual frameworks that guide the analysis and internal methodological standards in economic modelling projects.
• Conduct, supervise, oversee and quality assure the development of cost-effectiveness models, budget impact models, local adaptations, burden of illness etc, in collaboration with fellow technical analysts.
• Lead and oversee activities related to quality assurance (i.e. design and implementation of quality control procedures to ensure that deliverables are delivered at an excellent standard).
• Lead the development of slide decks, study reports, manuscripts, evidence dossiers, posters and other publications related to health economics and outcomes research.
• Proactively encourage and engage with interdisciplinary team working to scope new projects, research new and innovative methods in health economics and outcomes research and ensure consistency in the use of evidence across the life cycle of a multi-disciplinary project.
• Develop and maintain strong client relationships to ensure high client satisfaction, while keeping projects to time, budget and scope.
• Confidently interact with clients on a regular basis, being the main point of contact for assigned projects and able to lead client meetings and written communications that may be highly technical or sensitive in nature.
• Recognise, generate and lead on opportunities for the development of the business, including proposals for new projects.
• Lead, co-ordinate and supervise project teams, and provide mentorship and/or line management for less experienced staff.
• Undertake activities of continuous professional development and learning, inclusive of recognising and generating opportunities for further training of the staff.

The above is not an exhaustive list of duties, and you will be expected to perform different tasks as necessitated by the organisation's overall business objectives.

Essential requirements and qualifications

• Proven experience in health economics research, ideally within academia, consulting or the pharmaceutical sector
• Postgraduate qualification in a relevant discipline (e.g. Health Economics, Health Technology Assessment, Medical Statistics, Biostatistics, Mathematics, Econometrics)
• Excellent technical expertise in the development, audit and critical assessment of health economic evaluation and models, with experience in the development of economic models with various conceptual designs over a wide range of therapeutic areas.
• Demonstrated capability of mentoring less experienced health economists
• Demonstrated knowledge of health technology assessment methodology and processes
• A genuine interest and good understanding of statistical concepts, systematic review, evidence synthesis and critical appraisal of scientific literature
• Excellent quantitative, critical thinking and analytical skills, and able to review and synthesize large amounts of scientific information under a deadline
• An organised and methodological approach to planning and delivering work of high quality, inclusive of experience in project management
• Excellent oral and written communication skills and the ability to effectively engage with a wide-ranging audience and explain complex modelling techniques and results
• Interest in publication and conference attendance, with some publication history
• Excellent writing skills (for example, through development of presentations, reports, dossiers and/or manuscripts)
• Excellent accuracy and attention to detail, along with the ability to maintain high-quality deliverables given competing demands and changing deadlines
• Ability to work effectively in a team-oriented environment, as well as independently, leading small projects or subcomponents of larger projects
• High self-motivation, can-do attitude, optimistic outlook and leadership ability
• Takes initiative to learn new skills, and develops the skill set of others with less experience
• Proficiency using Microsoft Office and reference management software, with advanced skills in Excel

Desirable skills and experience

These are nice-to-have skills. Candidates who do not fulfil these requirements but are interested in this role are encouraged to apply.

• Experience with statistical and economic modelling software (e.g. R, Treeage, WinBUGS, SAS, Stata)
• Experience in analysing large datasets, understanding of clinical trial design and statistical methods
• Understanding of advanced statistical methods and concepts for evidence synthesis, e.g. indirect treatment comparison and network meta-analysis methods.
• Experience in and/or knowledge of clinical processes or trials
• Line management experience
• Business development experience

Application process

• Candidates successful in this first round will be contacted to attend an introductory phone call with a member of the Symmetron health economics team.

Please note

• This job is a full-time position based in our offices in Central London. Working from home is supported and organised around staff roles and responsibilities. Office attendance is in line with government guidance on COVID-19 restrictions.
• The successful candidate must have permission to work in the UK when starting their employment.
• No agencies, please.