Services

Evidence development

Systematic reviews

Systematic literature reviews are the foundation of all reimbursement submissions and sound policy decisions. We work with you to identify, evaluate and interpret evidence according to the highest international standards.

Rapid literature reviews

When systematic reviews are impossible because of tight timelines or the structure of the evidence, rapid literature reviews can be a pragmatic way to inform evidence-based decisions. We use diverse methodologies to conduct transparent and replicable reviews that meet your unique requirements and timeframes.

Evidence gap analyses

You may be uncertain where to focus your research and development efforts because you lack a deep understanding of the evidence gaps about safety and efficacy that need to be addressed to the satisfaction of HTA agencies. Drawing on methods from systematic literature reviews and health economic analyses, we can help you identify the research questions and corresponding analyses that will lead you to the story of greatest impact.

Other services include:
  • Horizon scanning
  • Outcome validation
  • Stakeholder analysis
Respiratory
Modelling survival after the clinical trials have ended
Author
Date
Policy and methods
Developing a framework for analysing the impact of patient-centred outcomes for achieving reimbursement in the UK
Author
Date
Cardiometabolic health
Evaluating the cost-effectiveness of a diagnostic device
Author
Date
Rare diseases
Gaining reimbursement for a drug targeting a rare disease
Author
Date
Oncology
Overcoming limited evidence to gain reimbursement for a blockbuster oncology drug
Author
Date
Dermatology
Overcoming the short-term bias in clinical evidence to compare long-term efficacy of psoriasis treatments
Author
Date
Dermatology
Validating comparisons of disease treatments in the absence of head-to-head trials
Author
Date
Neurology & mental health
Evaluating the cost-effectiveness of a medical device
Author
Date

Stay in touch

Subscribe to Symmetron and stay up to date with recent news and announcements.

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
This is a testimonial. This is a testimonial. This is a testimonial. This is a testimonial. This is a testimonial.
This is a testimonial. This is a testimonial. This is a testimonial. This is a testimonial. This is a testimonial.
“The team went above and beyond our expectations for our project. We were grateful that Symmetron was able to meet our deadlines, and to deliver a very large volume of work”
“One of the most efficient partnerships I’ve had with an external group.”
“Symmetron has expertise in all areas, including project management, SLRs, NMAs, economic modelling and a good relationship with the medical writer.”
“Our expectations were met, and the project was handled at the highest level."
Modelling survival after the clinical trials have ended
Modelling survival after the clinical trials have ended
Developing a framework for analysing the impact of patient-centred outcomes for achieving reimbursement in the UK
Developing a framework for analysing the impact of patient-centred outcomes for achieving reimbursement in the UK
Evaluating the cost-effectiveness of a diagnostic device
Evaluating the cost-effectiveness of a diagnostic device
Gaining reimbursement for a drug targeting a rare disease
Gaining reimbursement for a drug targeting a rare disease
Overcoming limited evidence to gain reimbursement for a blockbuster oncology drug
Overcoming limited evidence to gain reimbursement for a blockbuster oncology drug
Overcoming the short-term bias in clinical evidence to compare long-term efficacy of psoriasis treatments
Overcoming the short-term bias in clinical evidence to compare long-term efficacy of psoriasis treatments
Validating comparisons of disease treatments in the absence of head-to-head trials
Validating comparisons of disease treatments in the absence of head-to-head trials
Evaluating the cost-effectiveness of a medical device
Evaluating the cost-effectiveness of a medical device