Who we are

Meet the team

Laura Sawyer, MSc

Scientific Director

Laura specialises in health economic modelling and evidence synthesis. As Associate Director of Health Economics at Symmetron, she enjoys being involved in all aspects of the company. Laura has managed a wide variety of projects and is happiest diving into the details and tackling the technical and strategic challenges posed by complex problems.

Before joining Symmetron in 2012, Laura worked at the National Guideline Centre where she developed original decision models to inform NICE guidance. Her research, much of it published, covers a range of disease areas including psoriasis, epilepsy, bipolar disorder, rheumatoid arthritis, inflammatory bowel disease and cardiovascular diagnostics.

Laura received her MSc, with merit, in Health Policy, Planning and Financing, a degree offered jointly by the London School of Hygiene and Tropical Medicine and London School of Economics. Laura originally graduated from Rice University in Houston, Texas in 2006, achieving a BA in sociology and gender studies. Laura has served as a board member of the ISPOR South Africa chapter since 2016.

Clinical guidelines

National Institute for Health and Care Excellence. Bedwetting in under 19s. Clinical guideline 111 2010 [updated 10 Dec 2018. Available from: https://www.nice.org.uk/guidance/cg111.

National Institute for Health and Care Excellence. Chest pain of recent onset: assessment and diagnosis. Clinical guideline 95 2010 [updated 10 Dec 2018. Available from: https://www.nice.org.uk/guidance/cg95.

National Institute for Health and Care Excellence. Epilepsies: diagnosis and management. Clinical guideline 137 2012 [updated 10 Dec 2018. Available from: https://www.nice.org.uk/guidance/cg137.

National Institute for Health and Care Excellence. Psoriasis: assessment and management. Clinical guideline 153 2012 [updated 10 Dec 2018. Available from: https://www.nice.org.uk/guidance/cg153.

Targeted systemic therapies for psoriatic arthritis: a systematic review and comparative synthesis of short-term articular, dermatological, enthesitis and dactylitis outcomes
Arthritis and immunology
Targeted systemic therapies for psoriatic arthritis: a systematic review and comparative synthesis of short-term articular, dermatological, enthesitis and dactylitis outcomes
Laura Sawyer, MSc
2022
An economic evaluation of vagus nerve stimulation as an adjunctive treatment to anti-seizure medications for the treatment of drug-resistant epilepsy in England
Neurology & mental health
An economic evaluation of vagus nerve stimulation as an adjunctive treatment to anti-seizure medications for the treatment of drug-resistant epilepsy in England
Laura Sawyer, MSc
Vicki Pollit, MSc
2021
Cost-effectiveness of an insertable cardiac monitor to detect atrial fibrillation in patients with cryptogenic stroke
Cardiometabolic health
Cost-effectiveness of an insertable cardiac monitor to detect atrial fibrillation in patients with cryptogenic stroke
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2020
Assessing the Quality and Coherence of Network Meta-Analyses of Biologics in Plaque Psoriasis: What Does All This Evidence Synthesis Tell Us?
Dermatology
Assessing the Quality and Coherence of Network Meta-Analyses of Biologics in Plaque Psoriasis: What Does All This Evidence Synthesis Tell Us?
Laura Sawyer, MSc
2020
Targeted therapies for patients with moderate-to-severe psoriasis: a systematic review and network meta-analysis of PASI response at 1 year
Dermatology
Targeted therapies for patients with moderate-to-severe psoriasis: a systematic review and network meta-analysis of PASI response at 1 year
Laura Sawyer, MSc
2020
Cost-Effectiveness of Vagus Nerve Stimulation for Treatment-Resistant Depression in the United Kingdom
Neurology & mental health
Cost-Effectiveness of Vagus Nerve Stimulation for Treatment-Resistant Depression in the United Kingdom
Laura Sawyer, MSc
2020
Cost per PASI-75 responder of calcipotriol plus betamethasone dipropionate cutaneous foam versus nonbiologic systemic therapies for the treatment of plaque psoriasis in seven European countries.
Dermatology
Cost per PASI-75 responder of calcipotriol plus betamethasone dipropionate cutaneous foam versus nonbiologic systemic therapies for the treatment of plaque psoriasis in seven European countries.
Laura Sawyer, MSc
2020
Tofacitinib for the treatment of moderately to severely active ulcerative colitis: a systematic review, network meta-analysis and economic evaluation.
Arthritis and immunology
Tofacitinib for the treatment of moderately to severely active ulcerative colitis: a systematic review, network meta-analysis and economic evaluation.
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2019
Assessing the relative efficacy of interleukin-17 and interleukin-23 targeted treatments for moderate-to-severe plaque psoriasis: A systematic review and network meta-analysis of PASI response
Dermatology
Assessing the relative efficacy of interleukin-17 and interleukin-23 targeted treatments for moderate-to-severe plaque psoriasis: A systematic review and network meta-analysis of PASI response
Laura Sawyer, MSc
2019
Cost effectiveness of an insertable cardiac monitor in a high-risk population in the UK
Cardiometabolic health
Cost effectiveness of an insertable cardiac monitor in a high-risk population in the UK
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
Claudia Rinciog, MSc
2019
Long-term efficacy of novel therapies in moderate-to-severe plaque psoriasis: a systematic review and network meta-analysis of PASI response
Dermatology
Long-term efficacy of novel therapies in moderate-to-severe plaque psoriasis: a systematic review and network meta-analysis of PASI response
Laura Sawyer, MSc
2018
The comparative efficacy of brodalumab in patients with moderate-to-severe psoriasis: a systematic literature review and network meta-analysis
Dermatology
The comparative efficacy of brodalumab in patients with moderate-to-severe psoriasis: a systematic literature review and network meta-analysis
Laura Sawyer, MSc
2018
A Network Meta-Analysis to Evaluate The Efficacy of Brodalumab in the Treatment of Moderate-To-Severe Psoriasis
Dermatology
A Network Meta-Analysis to Evaluate The Efficacy of Brodalumab in the Treatment of Moderate-To-Severe Psoriasis
Laura Sawyer, MSc
2017
Assessing the Longer-Term Efficacy of Biologic Therapies and Apremilast for Patients with Moderate-To-Severe Psoriasis: A Systematic Review and Network Meta-Analysis
Dermatology
Assessing the Longer-Term Efficacy of Biologic Therapies and Apremilast for Patients with Moderate-To-Severe Psoriasis: A Systematic Review and Network Meta-Analysis
Laura Sawyer, MSc
2017
Cost-Effectiveness Analysis of Alternative Antiviral Strategies for the Treatment of HBeAg-Positive and HBeAg-Negative Chronic Hepatitis B in the United Kingdom
Arthritis and immunology
Cost-Effectiveness Analysis of Alternative Antiviral Strategies for the Treatment of HBeAg-Positive and HBeAg-Negative Chronic Hepatitis B in the United Kingdom
Laura Sawyer, MSc
2015
Tocilizumab in Methotrexate-Naive Rheumatoid Arthritis – A Cost-Utility Model for Slovakia
Arthritis and immunology
Tocilizumab in Methotrexate-Naive Rheumatoid Arthritis – A Cost-Utility Model for Slovakia
Laura Sawyer, MSc
Alex Diamantopoulos, MSc
2015
Biological therapies for the treatment of severe psoriasis in patients with previous exposure to biological therapy: a cost-effectiveness analysis
Dermatology
Biological therapies for the treatment of severe psoriasis in patients with previous exposure to biological therapy: a cost-effectiveness analysis
Laura Sawyer, MSc
2015
Tocilizumab in the Treatment of Rheumatoid Arthritis: A Cost-Effectiveness Analysis in the UK
Arthritis and immunology
Tocilizumab in the Treatment of Rheumatoid Arthritis: A Cost-Effectiveness Analysis in the UK
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2014
Cost-effectiveness of asenapine in the treatment of bipolar I disorder patients with mixed episodes
Rare diseases
Cost-effectiveness of asenapine in the treatment of bipolar I disorder patients with mixed episodes
Laura Sawyer, MSc
Claudia Rinciog, MSc
2014
Mabthera (Rituximab) for the Treatment of Severe Granulomatosis With Polyangiitis (Gpa) and Microscopic Polyangiitis (Mpa) – A Cost-Utility Model for the United Kingdom
Rare diseases
Mabthera (Rituximab) for the Treatment of Severe Granulomatosis With Polyangiitis (Gpa) and Microscopic Polyangiitis (Mpa) – A Cost-Utility Model for the United Kingdom
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2014
Efficacy Of Novel Dmards In Early Active Rheumatoid Arthritis: An Indirect Comparison
Arthritis and immunology
Efficacy Of Novel Dmards In Early Active Rheumatoid Arthritis: An Indirect Comparison
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2014
Topical therapies for the treatment of plaque psoriasis: systematic review and network meta-analyses
Dermatology
Topical therapies for the treatment of plaque psoriasis: systematic review and network meta-analyses
Laura Sawyer, MSc
2013
Tocilizumab in Polyarticular Juvenile Idiopathic Arthritis – A Cost-Utility Model for the United Kingdom
Arthritis and immunology
Tocilizumab in Polyarticular Juvenile Idiopathic Arthritis – A Cost-Utility Model for the United Kingdom
Laura Sawyer, MSc
Alex Diamantopoulos, MSc
2013
Topical therapies for the treatment of localized plaque psoriasis in primary care: a cost-effectiveness analysis. Br J Dermatol
Dermatology
Topical therapies for the treatment of localized plaque psoriasis in primary care: a cost-effectiveness analysis. Br J Dermatol
Laura Sawyer, MSc
2013
Cost-Effectiveness of Asenapine in the Treatment of Bipolar Disorder I Patients with Mixed Episodes
Neurology & mental health
Cost-Effectiveness of Asenapine in the Treatment of Bipolar Disorder I Patients with Mixed Episodes
Laura Sawyer, MSc
Claudia Rinciog, MSc
2013
Validity of cost and utility results?
Policy and methods
Validity of cost and utility results?
Alex Diamantopoulos, MSc
Laura Sawyer, MSc
2012
Diagnosis and management of the epilepsies in adults and children: summary of updated NICE guidance
Policy and methods
Diagnosis and management of the epilepsies in adults and children: summary of updated NICE guidance
Laura Sawyer, MSc
2012
Guideline Development G. Assessment and management of psoriasis: summary of NICE guidance
Policy and methods
Guideline Development G. Assessment and management of psoriasis: summary of NICE guidance
Laura Sawyer, MSc
2012
Guideline Development G. Management of bedwetting in children and young people: summary of NICE guidance
Policy and methods
Guideline Development G. Management of bedwetting in children and young people: summary of NICE guidance
Laura Sawyer, MSc
2010

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Training and workshops
Statistical analysis
Medical writing
Health technology assessment
Health economic modelling
Evidence development